Gene name:
CTSK (CTSO;CTSO2) ;
Protein name:
Cathepsin K ;
Alternative:
Cathepsin O2 ;Cathepsin O ;Cathepsin X ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
Subcellular Location:
Lysosome
Protein Attributes:
50:
MWGLKVLLLP | VVSFALYPEE | ILDTHWELWK | KTHRKQYNNK | VDEISRRLIW |
100:
EKNLKYISIH | NLEASLGVHT | YELAMNHLGD | MTSEEVVQKM | TGLKVPLSHS |
150:
RSNDTLYIPE | WEGRAPDSVD | YRKKGYVTPV | KNQGQCGSCW | AFSSVGALEG |
200:
QLKKKTGKLL | NLSPQNLVDC | VSENDGCGGG | YMTNAFQYVQ | KNRGIDSEDA |
250:
YPYVGQEESC | MYNPTGKAAK | CRGYREIPEG | NEKALKRAVA | RVGPVSVAID |
300:
ASLTSFQFYS | KGVYYDESCN | SDNLNHAVLA | VGYGIQKGNK | HWIIKNSWGE |
329:
NWGNKGYILM | ARNKNNACGI | ANLASFPKM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Dog
Pig
Chicken
Bovine
Rabbit
ELISA Kit for Human Cathepsin K
ELISA Kit for Human Cathepsin K
ELISA Kit for Human Cathepsin K
ELISA Kit for Human Cathepsin K
ELISA Kit for Human Cathepsin K
ELISA Kit for Human Cathepsin K
ELISA Kit for Human Cathepsin K
ELISA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
CLIA Kit for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Polyclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Monoclonal Antibody for Human Cathepsin K
Protein for Human Cathepsin K
Protein for Human Cathepsin K
Protein for Human Cathepsin K
Protein for Human Cathepsin K
Protein for Human Cathepsin K
Protein for Human Cathepsin K
Protein for Human Cathepsin K
Protein for Human Cathepsin K
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Blood .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Bone .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Osteoclastoma .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Spleen .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
6.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
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more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Skin .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS)
10.
"Design of potent and selective human cathepsin K inhibitors that span the active site."
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Veber D.F.
more...
Proc. Natl. Acad. Sci. U.S.A.94:14249-14254(1997)
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Cited for : X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
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Cited for : X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF ZYMOGEN FORM
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Cited for : X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS)
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Cited for : VARIANT PKND ARG-146
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Cited for : VARIANT PKND VAL-277
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Cited for : VARIANT PKND GLU-79
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Cited for : VARIANTS PKND GLU-79 AND PRO-309